Vitamin B12 deficiency symptoms: Three signs you can see on your skin

Dr Dawn Harper on signs of vitamin B12 and vitamin D deficiency

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For every 10 people over the age of 60, two of them are likely to be deficient in vitamin B12; this could be due to various factors. Could you be affected? The American Academy of Family Physicians (AAFP) identified three signs you can see on your skin when you’re deficient in vitamin B12. Clinical manifestations include: hyperpigmentation, vitiligo and jaundice.

Hyperpigmentation

The American Osteopathic College of Dermatology (AOCD) explained hyperpigmentation is when patches of skin become darker in colour than the surrounding skin.

This skin condition can affect the skin colour of any race, and is typically seen on older people as “liver” spots.

Vitiligo

The AOCD explained vitiligo is when patches of skin lose their pigmentation, leaving white patches.

The condition can be inherited in one third of cases, and it’s progressive in nature.

This means white patches may begin in the hands, feet and face, and then spread to other parts of the body.

Jaundice

The NHS explained jaundice is when the skin and whites of the eyes turn yellow.

What can cause a vitamin B12 deficiency?

Aside from dietary restrictions, such as veganism, some people may have pernicious anaemia.

Pernicious anaemia is an autoimmune condition where the body can’t absorb vitamin B12.

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The long-term use of certain medications has also been linked to a vitamin B12 deficiency.

For example diabetics taking 850mg of metformin three times daily, compared to placebo, had an increased risk of vitamin B12 deficiency.

This was replicated with long-term use of proton pump inhibitors (PPIs), prescribed to relieve GERD symptoms.

A vitamin B12 deficiency was also more likely in those aged 75 and older, or those who abuse alcohol.

Other symptoms of a vitamin B12 deficiency

As well as skin manifestations of a vitamin B12 deficiency, there is the gastrointestinal issue of glossitis.

Glossitis is a sore or white tongue, clarified the national health body.

A vitamin B12 deficiency can also lead to “neuropsychiatric” symptoms, such as irritability, cognitive and olfactory impairment.

The AARF added that it can also lead to areflexia, which is when the muscles don’t respond to stimuli.

Those suspected of a vitamin B12 deficiency may be able to get a blood test to confirm a diagnosis.

Medical staff don’t usually screen for a vitamin B12 deficiency unless there are reasons to believe a patient may be deficient in the vitamin.

If you’re concerned you may be affected, it’ll be wise to discuss your concerns with your doctor.

Treatments are available, which may involve intramuscular injections of vitamin B12.

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